Molecular Biology – Part 3: RNA Processing and Translation

Offered By

Available now till 2024-05-28

48.00 Educational Hours

Advanced

Language :

English

Translations

11 Skills

About this Course

In Part 3 of 7.28x, you’ll explore translation of mRNA to protein, a key part of the central dogma of biology. Do you know how RNA turnover or RNA splicing affects the outcome of translation? Although not official steps in the central dogma, the mechanisms of RNA processing strongly influence gene expression.

Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?

Take a behind-the-scenes look at modern molecular biology, from the classic experimental events that identified the proteins and elements involved in translation and RNA splicing to cutting-edge assays that apply the power of genome sequencing. Do you feel confident in your ability to design molecular biology experiments and interpret data from them? We've designed the assessments in this course to build your experimental design and data analysis skills.

Let’s explore the limits of our current knowledge about the translation machinery and mechanisms of RNA turnover and splicing. If you are up for the challenge, join us in 7.28.3x Molecular Biology: RNA Processing and Translation.

Instructors

Stephen P. Bell

Steve Bell is a Professor of Biology in the Department of Biology at MIT and an HHMI Investigator. Steve and his lab study the regulation of eukaryotic replication using biochemical, genetic, and molecular biology approaches. He has received the institute-wide Everett Moore Baker Memorial Teaching Award as well as a School of Science Teaching Prize for Excellence in Undergraduate Education. Along with Tania, Steve co-authored a popular molecular biology textbook with James Watson.

Tania A. Baker

Tania Baker is an E. C. Whitehead Professor of Biology and an HHMI Investigator. Tania recently received the Arthur Kornberg and Paul Berg Lifetime Achievement Award for her research in replication and AAA+ unfoldases, which remove potentially toxic proteins. Tania has also been recognized for her commitment to teaching as a recipient of the Margaret MacVicar Faculty Fellowship and a School of Science Teaching Prize for Excellence in Undergraduate Education. In addition to authoring the textbook with Steve, as a graduate student, Tania co-authored a well-known textbook on DNA replication with Arthur Kornberg.

Mary Ellen Wiltrout

Mary Ellen earned her Ph.D. from the Department of Biology at MIT in 2009 and returned in 2013 to create 7.00x Introduction to Biology with Professor Eric Lander. Mary Ellen oversees the execution and evolution of MIT Department of Biology’s digital learning strategy. The group develops digital learning content for MIT students, advises evidence-based teaching practices, creates MITx courses, and studies the impact of design on learner engagement in their research. In 2016, Mary Ellen earned the MIT Infinite Mile Award. In 2019, their work received a silver award at the Reimagine Education science of learning category.

Sera Thornton

Dr. Sera Thornton was an MITx Digital Learning Fellow in the Department of Biology at MIT from 2014 to 2017. In conjunction with her role as a core member of the MITx Biology course development team, Sera curated and created many of the graphics for MITx Biology courses, including animating the lecture video inserts for MITx 7.28x. She previously completed her Ph.D. studying epigenetic gene regulation in stem cell lineage commitment and differentiation in the Boyer lab at MIT.

Swati Carr

Dr. Swati Carr is a Digital Learning Lab Fellow in the Department of Biology at MIT. As part of her role as a core member of the MITx Biology course development team, Swati develops and tests assessments for their courses. She completed her Ph.D. by developing methodology for improving the predictability of engineered genetic device behavior in the Densmore lab at Boston University.