How to analyze a microbiome
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نبذة عن المقرر
Microorganisms play a major role in the biosphere and within our bodies, but only a tiny fraction has been cultured so far. Microbiome data, that is the genetic information of microorganisms, is therefore an important window into the hidden microbial world.
Microbiome data analysis elucidates the composition of microbial communities and how it changes in response to the environment. When analyzing sequencing data, we learn whether microbial diversity differs across conditions and identify links between microbes. In brief, microbiome data analysis gives us a first idea of how a microbial ecosystem works.
This course will illustrate with the help of real-world example data how to carry out typical analysis tasks, such as comparing microbial composition and diversity, clustering samples and computing associations. If you plan to work with microbiome data, this course will get you up to speed.
The instructors are experienced bioinformaticians who are internationally known for their analysis of large-scale microbiome data sets.
المدربين
Karoline Faust
Karoline Faust is Assistant Professor in Microbiological Bioinformatics at the Department of Microbiology, Immunology and Transplantation at KU Leuven. She completed her PhD in 2010 and is leading the group of Microbial Systems Biology since 2016. She is an experienced bioinformatician and internationally known for her analysis of large-scale microbiome data sets.
Sam Röttjers
Sam Röttjers is a PhD student of Karoline and works on method development for noisy networks. Sam focuses on the top-down side of microbiome research and has worked with data from arthropod endosymbionts, the human gut and ocean time series. His main goal is to translate concepts from theoretical ecology and network theory to association networks in a way that deals with the inherently low accuracy of these networks.
Anna Krzynowek
Anna is a PhD student in the lab of Prof. Karoline Faust at KU Leuven. Her project focuses on the analysis of microbiome of a freshwater flea Daphnia magna and its ability to biodegrade complex polymers. Before joining KU Leuven, Anna earned her MSc degree in Chemistry at Heriot Watt University where she investigated novel microalgae for synthesis of high-value compounds.
